| 书目名称 | Histone Methyltransferases | | 副标题 | Methods and Protocol | | 编辑 | Raphaël Margueron,Daniel Holoch | | 视频video | | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .This volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities .in vitro,. generating chromatin substrates, auto-methylation, quantification of metabolites, protein purification, crystallization, X-ray structure, cryogenic electron microscopy, assessing genome-wide patterns, CUT&Tag in mouse embryonic tissues, chemical biology approaches, peptide SPOT arrays, nascent chromatin capture, ectopic protein tethering, computational models, and development of methyltransferase inhibitors. Written in the format of the highly successful .Methods in Molecular Biology .series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols... ..Authoritative and cutting-edge, .Histone Methyltransferases: Methods and Protocols .aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.. | | 出版日期 | Book 2022 | | 关键词 | chromatin compaction; automethylation; substrate interaction; X-ray crystallography; peptide probes | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-0716-2481-4 | | isbn_softcover | 978-1-0716-2483-8 | | isbn_ebook | 978-1-0716-2481-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
The information of publication is updating
|
|
发表于 2025-3-21 16:31:45
