Titlebook: Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders; Shabir Ahmad Ganai Book 2019 Springer Nature Singapore Pte Ltd. 2019

悠然

Epigenetics and its Implications in Neurological Disorders,tions of histone and non-histone substrates. Epigenetic dysregulation due to aberrant activity of these players alters homeostasis provoking neurological complications. Here I discuss the amendments of the definition of epigenetics over time and the various post-translational modifications that hist

Magnificent

Epigenetic Enzymes and Drawbacks of Conventional Therapeutic Regimens, acetylation, methylation, phosphorylation etc. Methylation of DNA cytosine is also regarded as epigenetic modifications as it causes gene repression by recruiting HDACs. This chapter gives the bird’s eye view of writers and erasers of epigenetic modifications. Among the writers, special emphasis ha

Erythropoietin

否决

coltish

HDAC Inhibitors as Novel Therapeutic Option Against Therapeutically Challenging Neurological Disordulation and as such are emerging as promising therapeutic agents for vanquishing neurological disorders. Here we discuss the marvellous therapeutic effect of various HDACi against neurological disorders including Alzheimer’s disease, Parkinson’s disease, and epilepsy. The underlying molecular player

Terrace

愤愤不平

thwart

牌带来

Future Directions, a particular neurological complication, neuronal death or damage is not general, but specific brain regions are particularly affected. Different focal pathologies are exhibited by distinct disorders, and thus gaining insights regarding the region-specific effects of these inhibitors is requisite fo

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