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Titlebook: Histiocytic Disorders; Oussama Abla,Gritta Janka Book 2018 Springer International Publishing AG 2018 langerhans cell Histiocytosis.hemopha

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发表于 2025-3-21 18:36:55 | 显示全部楼层 |阅读模式
书目名称Histiocytic Disorders
编辑Oussama Abla,Gritta Janka
视频video
概述First comprehensive book on histiocytic disorders in over ten years.Features the most recent advances and treatment strategies for common and uncommon histiocytic disorders.Written by international ex
图书封面Titlebook: Histiocytic Disorders;  Oussama Abla,Gritta Janka Book 2018 Springer International Publishing AG 2018 langerhans cell Histiocytosis.hemopha
描述This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment o
出版日期Book 2018
关键词langerhans cell Histiocytosis; hemophagocytic lymphohistiocytosis; macrophage activation syndrome; JXG
版次1
doihttps://doi.org/10.1007/978-3-319-59632-7
isbn_softcover978-3-319-86667-3
isbn_ebook978-3-319-59632-7
copyrightSpringer International Publishing AG 2018
The information of publication is updating

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发表于 2025-3-21 21:37:44 | 显示全部楼层
Adult Langerhans Cell Histiocytosismary pulmonary LCH, in almost all cases associated with smoking, is a common presenting pattern in adults and has particular clinico-radiographic and treatment features that warrant its characterization as a separate entity.
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Classification, Clinical Manifestations, and Diagnostics of HLHrucial for appropriate therapeutic management. Clinical diagnosis of an HLH episode, followed by sequential immunological testing, and genetic diagnosis provide the basis for a rapid decision on hematopoietic stem cell transplantation indicated in patients with primary HLH.
发表于 2025-3-22 18:38:34 | 显示全部楼层
Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosisct issues including the frequent development of mixed chimerism. Patients with HLH are also challenging due to the potential for recurrence of HLH post HCT. Novel therapies, including interferon neutralization and genetic therapies, may facilitate initial and definitive therapy for future patients with HLH.
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Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein-Barr Virusncreased awareness has led to improved recognition as well as research into these as yet poorly understood disorders. We discuss current insights into the clinical manifestations, prognostic features, biology, and treatment approaches for malignancy- and EBV-associated HLH.
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Oussama Abla,Gritta JankaFirst comprehensive book on histiocytic disorders in over ten years.Features the most recent advances and treatment strategies for common and uncommon histiocytic disorders.Written by international ex
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