Titlebook: Histamine in Inflammation; Robin L. Thurmond Book 2010 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springe

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lle des Verjährungsbeginns anhand von FallgruppenDieses Buch analysiert die praxisrelevante Frage der Verjährung von Arzthaftungsansprüchen. In einem ersten Teil werden die dogmatischen Grundlagen der Verjährung dargestellt. Auf dieser Basis erfolgt eine Untersuchung der Voraussetzungen des Verjähru

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One Hundred Years of Histamine Research,isolated as a bacterial contaminant of an extract of ergot (1910), the elucidation of its role in health and disease and its molecular mechanism of action have been continuous, reflecting the application of advances in scientific knowledge, technology and therapeutics over the last 100 years.. It ap

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Histamine Synthesis and Lessons Learned from Histidine Decarboxylase Deficient Mice,ine synthesis, and the activity of histamine in vivo as clarified using HDC gene deficient mice (HDC-KO). The research of the regulatory mechanism of histamine synthesis has been focused on transcriptional and posttranslational aspects. The generation of HDC-KO mice clarified several new pathophysio

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The Role of Histamine in Ocular Allergy,, histamine is perhaps the best characterized. This monoamine is released by sensitized mast cells upon exposure to allergen and causes symptoms such as redness and tearing. Histamine may also recruit immune cells that can cause long-term damage to ocular surfaces. In this chapter we will discuss th

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The Role of Histamine in Asthma,ne H. receptor, have failed to demonstrate a significant role for histamine in asthma. Novel immunomodulatory roles for histamine and the discovery of a novel histamine receptor, the histamine H. receptor, have resulted in a reassessment of its importance in asthma.

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Antihistamines in the Treatment of Urticaria,he avoidance of eliciting factors and the elimination of underlying causes is not feasible. In nearly all subtypes histamine released by mast cells plays apredominant role. For symptomatic relief second generation nonsedating histamine H. receptor (H.R)-antihistamines are, therefore, the first choic

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Histamine, Immune Cells and Autoimmunity,protein-coupled receptors (H.R, H.R, H.R and H.R), intracellular histamine binding sites (most likely members of the cytochrome P450 family) as well as a membrane transporter (Organic Cation Transporter; OCT3) expressed in various immunocompetent cells, it can entertain a complex network of interact