Titlebook: Hippocampal Microcircuits; A Computational Mode Vassilis Cutsuridis,Bruce P. Graham,Imre Vida Book 2018Latest edition Springer Nature Switz

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SPASM

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Systematic Data Mining of Hippocampal Synaptic Propertiesnnections” among neuron types. Extensive literature mining revealed electrophysiological properties for approximately 50% of these potential synapses at neuron-type level in peer-reviewed publications. In these cases, we extract information about synaptic amplitude, kinetics, and, when available, sh

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Spatiotemporal Patterns of Granule Cell Activity Revealed by a Large-Scale, Biologically Realistic Mterns of activity generated by the dentate gyrus. The results show that the topographical projection of axons between the entorhinal cortex and the dentate granule cells organizes the postsynaptic population into subgroups of neurons that exhibit correlated firing expressed as spatiotemporal cluster

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Picks-Disease

Models of Rate and Phase Coding of Place Cells in Hippocampal Microcircuitsnd beyond this point it decreases again (Fig. 1 medium; Harris etal. 2002; Mehta etal. 2002). Place cells have also been shown to systematically shift their phase of firing to earlier phases of the theta rhythm as the animal transverses the place field (a phenomenon known as theta phase precession)

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Computational Models of Grid Cell Firingures of each. These models are intended to be both parsimonious and make testable predictions. We discuss the strengths and weaknesses of each model and the predictions they make for future experimental manipulations of the grid cell network in vivo.

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Modeling Synaptic Plasticity in Hippocampus: A Calcium-Based Approachex. Furthermore, we use the model to predict memory decay times and plasticity in the presence of uncorrelated Poisson firing. The calcium model provides a mechanistic understanding of how various stimulation protocols provoke specific synaptic changes through the dynamics of calcium concentration a

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