Titlebook: Highly Selective Separations in Biotechnology; G. Street Book 1994 Chapman & Hall 1994 biochemistry.biotechnology.chemistry.chromatography

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Affinity precipitation,sses operated on a large industrial scale already. Precipitation is usually based on aggregation caused by some non-specific factor, e.g. hydrophobic interactions, and therefore it is unrealistic to expect any degree of selectivity. Precipitation by additions of salt or organic solvents (.), polymer

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Affinity partitioning,s and cells. Purification of proteins by extraction from one aqueous phase to another (also water-rich) phase has found increasing use for large-scale processes due to the ease of scaling up liquid-liquid extraction procedures. The basis for such extractions of proteins is the so-called aqueous two-

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The chemistry and engineering of affinity chromatography,niques (.; .; .; .; .; .; .; .; .; .) in which biochemicals are bonded to a solid support and undergo specific and reversible interactions with a substrate to be purified. In the process the substrate forms a stable, reversible association complex with the support-bound biospecific ligands. The resu

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