Titlebook: High-Risk Breast Cancer; Therapy Joseph Ragaz,Irving M. Ariel Book 1991 Springer-Verlag Berlin Heidelberg 1991 Breast Cancer.Brustkrebs.Kre

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o the global aspects of cancer management. To follow and understand all the new developments is becoming a major challenge. For this reason, the editors decided to bring together a group of top researchers in breast cancer to provide a comprehensive, yet readable conceptual review of the state of th

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The Role of Surgery in the Treatment of Breast Cancer: Historical Review and Current Status simple statement is made concerning treatment: “There is no treatment.” This was the first separation of tumors of the breast (cancer) from inflammatory diseases or abscesses. Cauterization, “fine drill,”was used for abscesses, but no treatment whatsoever was advocated for the cancers.

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High-Risk Breast Cancer: Bilaterality predictive for the development of cancer in the opposite breast will be discussed. Management of the second breast will include comments on routine biopsy at the time of initial mastectomy, prophylactic contralateral mastectomy, and the role of bilateral prophylactic mastectomy.

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Book 1991al aspects of cancer management. To follow and understand all the new developments is becoming a major challenge. For this reason, the editors decided to bring together a group of top researchers in breast cancer to provide a comprehensive, yet readable conceptual review of the state of the art of b

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Dose Intensity of Chemotherapy in High-Risk Breast Cancerations of different drugs and alterations of schedules have failed to break this impasse. In fact, introduction of these combinations and schedules has probably obscured important dose-response relationships and contributed to the impasse.

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Therapeutic Highlights of High-Risk Breast Cancer: Comments Related to Surgery, Radiotherapy, and Hoe led to the downfall of the Halsted doctrine, which was made obsolete by ample evidence indicating that the same results can be achieved by conservative surgery. Furthermore, data showing that long-term survival is favorably influenced by systemic rather than loco-regional therapies confirm these observations.

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The Role of Radiation Therapy in High-Risk Breast Canceration therapy. For these patinets, successful therapy must maximize locoregional (LR) control without compromising cosmesis. Likewise, when adjuvant treatment is given after a mastectomy, or when radiotherapy is utilized as the primary treatment in locally advanced breast cancer, the probability of LR recurrence must be considered.