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Titlebook: Hierarchical Bottom-Up Methodology for Integrating Dynamic Ethynylhelicene Oligomers; Synthesis, Double He Nozomi Saito Book 2013 Springer

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书目名称Hierarchical Bottom-Up Methodology for Integrating Dynamic Ethynylhelicene Oligomers
副标题Synthesis, Double He
编辑Nozomi Saito
视频video
概述Nominated by Tohoku University as an outstanding Ph.D. thesis.Describes methodology to systematically obtain diverse synthetic homo- and hetero-double helix molecules using ethynylhelicene oligomers.B
丛书名称Springer Theses
图书封面Titlebook: Hierarchical Bottom-Up Methodology for Integrating Dynamic Ethynylhelicene Oligomers; Synthesis, Double He Nozomi Saito Book 2013 Springer
描述In biological systems, molecules hierarchically form ordered assemblies and macroscopic substances, as exemplified by the assembly of proteins. The development of such systems using oligomeric macromolecules obtained by organic synthesis can provide insights into biological phenomena and will lead to the creation of new materials. In this regard, synthetic double helix molecules are attractive subjects of study because they have an important structural motif that appears widely in nature and can exhibit dynamic structural change. This thesis describes an unprecedented bottom-up approach using synthetic ethynylhelicene oligomers, which form dynamic double helices in organic media. Oligomer synthesis, homo- and hetero-double helix formation, and higher assembly formation due to intercomplex interactions are documented. The hierarchical assembly formation is a cogent reminder of the assembly of biological proteins that create living creatures. Also notable here is the demonstration of a methodology of providing diverse hetero-double helices and their higher assemblies by changing the combination of oligomers, which can be another advantage of this synthetic system.
出版日期Book 2013
关键词Bottom-up Approach; Chiral Discrimination; Double Helix; Helicene; Oligomeric Macromolecules; Pseudoenant
版次1
doihttps://doi.org/10.1007/978-4-431-54514-9
isbn_softcover978-4-431-56371-6
isbn_ebook978-4-431-54514-9Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer Japan 2013
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Nozomi Saitocommon of all human disease s such as ringworm or dermatophytosis, superficial . infections, and pityriasis versicolor. These are infections seen in all climates. Some such as tinea corporis are more common in the tropics, whereas foot infection is seen in all countries, and onychomycosis or fungal
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orale problemen of tandheelkundige en mondhygiënische behandelingen kan van levensbelang zijn bij patiënten met ziekten die gepaard gaan met een verminderde afweer of bij patiënten bij wie de verminderde afweer medicamenteus wordt nagestreefd. Beide situaties kunnen zich ook bij één patiënt voordoen
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Homo-Double-Helix Formation of Ethynylhelicene Oligomers Possessing Various Side Chains, notable effects on the thermodynamic stability of homo-double helices in organic media. This observation can be explained by the arrangement of soft/hard moieties: A regular alternating arrangement of soft/hard and electron-rich/deficient moieties can form a rigid aggregate, which results in stable
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Hetero-Double-Helix Formation of Pseudoenantiomeric Ethynylhelicene Oligomers,ive aggregation can be utilized to control the properties and functions of double-helix-based materials. To develop such materials, a methodology of providing diverse hetero-double helices is needed. Thus, hetero-double helix formation was examined using ethynylhelicene oligomers containing enantiom
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