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Titlebook: Herpetic Eye Diseases; Proceedings of the I P. C. Maudgal,L. Missotten Conference proceedings 1985 Dr W. Junk Publishers, Dordrecht 1985 di

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Genetic Influence from Chromosome 12 on Murine Susceptibility to Herpes Simplex Keratitisratopathy after HSV corneal inoculation. We found, using congenic strains of mice, that the Igh-1 gene locus exerts a powerful influence on the clinical expression of HSV infection. Mice with Igh-1e or Igh-1d phenotype routinely developed severe keratopathy after HSV corneal inoculation, while those
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Systemic Immune Responses after Ocular Antigenic Encounterpts are particularly well entrenched in traditional teaching, since the pioneering work of Medawar (1) and of Woodruff (2) demonstrated prolonged survival of allogenic transplants in these sites. In order to explain this relative unresponsiveness to antigen in these ocular sites, the notion of affer
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The Role of Virus-Infected Mononuclear Leukocytes in the Pathogenesis of Herpetic Chorioretinitis ofretinitis, which is one of the ocular manifestations of newborn herpetic infection, occurs after the skin infection, and, interestingly, HSV-2 has so far been the only isolate (1). In a previous report, we presented a newborn rabbit model of herpetic chorioretinitis which develops after skin infecti
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Experimental and Clinical Preliminary Study of Immunomodulators in the Treatment of Ocular Herpesor serious stromal and uveal lesions. Immunomodulators should be handled with paticular caution. The efficacy of diverses substances, such as isopri- nosine (1), and transfer factor (TF) (4, 6, 7), is still uncertain. However the use of an antiherpes specific transfer factor (TFd) (8) has decreased
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Subunit Vaccine Compared with Infection as Protection Against Experimental Herpes Simplex Keratitisgnosis of herpes simplex keratitis (HSK). Antivirals, however, have their limitations, for example; toxicity and the development of resistance, and an approach aimed at prevention is worth considering.
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towards greater integrative thinking about health and welfare. The global emergence of the concept of . has grown out of a number of sociopolitical, biomedical, and environmental pressures and influences, acting both internally on the theoretical limits of the health professions and disciplines, and
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