Titlebook: Heritage and the Sea; Volume 1: Maritime H Ana Crespo Solana,Filipe Castro,Nigel Nayling Book 2022 The Editor(s) (if applicable) and The Au

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,GIS Application for Sixteenth–Seventeenth Century Iberian Shipwrecks,sts new innovative ways of multidisciplinary research for historians, maritime archaeologists, forestry engineers, and others whose research may involve these topics, in order to take advantage of new technologies and to share information. The potential of database-oriented GIS in the study of marit

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Filipe Castro,Marijo Gauthier-Bérubé,Miguel Martinsogenic therapies. However, although it was possible to classify tumors into endothelial “poor” or “rich,” the technical limitations of sample selection, inter- and intra-observer variation, and conceptual biological problems were such that the technique could not be easily applied. Interest in gradi

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Filipe Castro,José Virgílio Pissarras are normally resident within a 3D macromolecular matrix, as provided by the vessel basement membrane and tissue stroma, respectively. Nevertheless, pericytes also form part of the newly formed vascular sprouts and fibroblasts surround and accompany these. In addition, vascular sprouts are commonly

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Patricia Schwindinger,Filipe Castro,Ana Crespo Solanaowth are not well defined. We recently isolated a novel endothelial stem/progenitor-like cells from the intima of adult murine blood vessels using the Hoechst method in which stem cell populations are identified as side populations. This vascular endothelial side population cell possesses colony-for

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Ana Crespo Solana,María José García-Rodrígueznd cytoskeletal dynamics, processes essential for tissue homeostasis, which therefore influence the viability and stability of new vascular networks. Most ETS proteins have been shown to activate transcription; however, a few can also act as transcriptional repressors. Several ETS factors can contro

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Ana Crespo Solana,Filipe Castro,Nigel Naylingls of hypoxia-induced angiogenesis in the retina and tumor, as well as acute hypoxia models using glass catfish, and discuss the usefulness of these models to elucidate key mechanisms behind pathological vascular disruption in retinopathy and cancer. At the end of the chapter we contextualize the hy

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Book 2022terdisciplinary interaction with dendroarchaeology. This synthesis combines ananalysis of historical sources, the systematic study of wreck-remains and material culture related to Iberian seafaring from the 15th to the 18th centuries, and the application of earth sciences, including dendrochronology

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Marcel Pujol i Hamelinkg angiogenesis in vivo continuously up to several weeks with high spatial and temporal resolution. In addition, after the termination of experiments, tissue samples can be excised easily and further examined by various in vitro methods (e.g., histology, immuno-histochemistry, and molecular biology).

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Koldo Trápaga Monchet, (2) protecting extremities from ischemic ulcers and other damage leading to limb loss, (3) providing relief from ischemic symptoms, and/or (4) improving functional capacity. Antiangiogenic agents may prove valuable in slowing or stopping cancers.

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