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Titlebook: Hepatocellular Carcinoma; Cellular and Molecul Rajagopal N. Aravalli,Clifford J. Steer Book 2014 The Author(s) 2014 Hepatocellular carcinom

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书目名称Hepatocellular Carcinoma
副标题Cellular and Molecul
编辑Rajagopal N. Aravalli,Clifford J. Steer
视频video
概述Includes supplementary material:
丛书名称SpringerBriefs in Cancer Research
图书封面Titlebook: Hepatocellular Carcinoma; Cellular and Molecul Rajagopal N. Aravalli,Clifford J. Steer Book 2014 The Author(s) 2014 Hepatocellular carcinom
描述.This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer. This book will be of interest to basic and clinical researchers, as well as to drug developers..
出版日期Book 2014
关键词Hepatocellular carcinoma; cirrhosis; gene expression; liver cancer; microRNA; tumor microenvironment
版次1
doihttps://doi.org/10.1007/978-3-319-09414-4
isbn_softcover978-3-319-09413-7
isbn_ebook978-3-319-09414-4Series ISSN 2194-1173 Series E-ISSN 2194-1181
issn_series 2194-1173
copyrightThe Author(s) 2014
The information of publication is updating

书目名称Hepatocellular Carcinoma影响因子(影响力)




书目名称Hepatocellular Carcinoma影响因子(影响力)学科排名




书目名称Hepatocellular Carcinoma网络公开度




书目名称Hepatocellular Carcinoma网络公开度学科排名




书目名称Hepatocellular Carcinoma被引频次




书目名称Hepatocellular Carcinoma被引频次学科排名




书目名称Hepatocellular Carcinoma年度引用




书目名称Hepatocellular Carcinoma年度引用学科排名




书目名称Hepatocellular Carcinoma读者反馈




书目名称Hepatocellular Carcinoma读者反馈学科排名




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Pathophysiology of HCC,s process. Interaction of a variety of cell types in the tumor stroma with extracellular matrix components lead to the acquisition of an abnormal phenotype that promotes tumor formation. It has also been demonstrated that hypoxia enhances progression, and metastasis of HCC. Activation of epithelial-
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Conclusions,llular processes and pathways. Thus, molecules such as Sorafenib and microRNAs, which can target multiple pathways simultaneously are necessary therapeutic tools for HCC. Lack of good molecular markers, effective early diagnosis, and an ideal animal model are also major hindrances to treat HCC. Ther
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ion is the preferred systemic treatment for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the androgen receptor (AR), a nuclear receptor transcription factor. ...Historically, the gene expression program mediated by the AR has been poorly understood. However,
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Rajagopal N. Aravalli,Clifford J. Steerion is the preferred systemic treatment for disseminated prostate cancer. Androgen action is exerted in target tissues via binding the androgen receptor (AR), a nuclear receptor transcription factor. ...Historically, the gene expression program mediated by the AR has been poorly understood. However,
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