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Titlebook: Hepatitis E Virus; Youchun Wang Book 20161st edition The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer

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Jun Zhang M.Sc.,Qinjian Zhao Ph.D.,Ningshao Xianto South African law in terms of the World Heritage Convention Act (Act No 49 of 1999), in 1999 inscribed the fossil hominid sites of Sterkfontein, Swartkrans, Kromdraai and environs (known as the Cradle of Humankind) for protection in terms of their ‘collective’ cultural heritage.
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Hepatitis E Virus,nces have been isolated from many different animals, including pigs, wild boars, deer, rabbits, bats, rats, chicken, and trout. All of these sequences have the same genomic organization, which contains open reading frames (ORFs) 1, 2, and 3, although their genomic sequences are variable. Some have p
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Epidemiology of Hepatitis E, developing and developed countries. There are two distinct epidemiologic patterns of hepatitis E. In areas with high disease endemicity, primarily developing countries in Asia and Africa, this disease is caused mainly by genotype 1 or 2 HEV, both of which transmit predominantly through contaminated
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Hepatitis E as a Zoonosis,from animals to humans. Genotyping of strains from hepatitis E virus-infected patients has revealed that these infections are not all caused by genotypes 1 or 2 but often by genotypes 3 or 4. Therefore, it is important to understand the striking difference between the spread of genotypes 1 and 2 in
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Genetic Evolution of Hepatitis E Virus,ly, a variety of genetically distinct HEV variants have also been isolated and identified from large numbers of animal species, including birds, rabbits, rats, ferrets, bats, cutthroat trout, and camels, among others. Furthermore, it has been reported that recombination in HEV genomes takes place in
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Immunobiology and Host Response to HEV,ogically mediated events should play important roles in its pathogenesis and infection outcomes. The anti-HEV antibody response was clarified when the major antigenic determinants on the ORF2 polypeptide were determined, which are located in its C-terminal portion. This subregion also forms the conf
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HEV Cell Culture,e considered to have high enough efficient for usage. Concentration of virus stocks, host cells, and medium components affect the culture efficient, and the genetic mutations during HEV passage were found to be associated with the increased virulence in cell culture. As an alternative method for tra
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