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Titlebook: Hepatitis C Virus Treatment; Highly Effective The Kazuaki Chayama Book 2017 Springer Science+Business Media Singapore 2017 Chronic Liver Di

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发表于 2025-3-21 17:27:13 | 显示全部楼层 |阅读模式
书目名称Hepatitis C Virus Treatment
副标题Highly Effective The
编辑Kazuaki Chayama
视频video
概述Introduces new therapies available for treating chronic hepatitis C.Describes Direct Acting Antiviral Agents (DAA), which have an excellent anti-viral effect on virus replication.Provides cutting-edge
图书封面Titlebook: Hepatitis C Virus Treatment; Highly Effective The Kazuaki Chayama Book 2017 Springer Science+Business Media Singapore 2017 Chronic Liver Di
描述.This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects. ..Hepatitis C Virus Treatment. offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the character
出版日期Book 2017
关键词Chronic Liver Disease; Infection; Interferon; Ribavirin; Direct Acting Antiviral Agents; DAA; Immunity; HCV
版次1
doihttps://doi.org/10.1007/978-981-10-2416-0
isbn_softcover978-981-10-9610-5
isbn_ebook978-981-10-2416-0
copyrightSpringer Science+Business Media Singapore 2017
The information of publication is updating

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Resistance-Associated Variants in the NS5A Region of HCV and Methods for the Detection,tion, have been shown to be crucial for the outcome of antiviral therapies, including NS5A inhibitors. Resistance-associated variants (RAVs) in the NS5A regions can be identified using cycling-prove real-time PCR, an invader assay, and/or direct sequencing. The significance of NS5A-RAVs is currently
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Detection of Antiviral Drug-Resistant Variants in Chronic Hepatitis C by Deep Sequencing,h screening for the presence of RAVs prior to therapy using direct sequencing or other methods, precise and accurate prediction is still not possible because the presence of RAVs at baseline does not guarantee treatment failure nor does the lack of preexisting RAVs preclude the emergence of resistan
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sich ernähren können. Diese erste, dem Thierleben vorausgegangene Pflanzenwelt bestand wahrscheinlich nur aus Zellenpflanzen des Wassers, deren kurze Lebensdauer und rasche Zersetzung die Ursache gewesen sein mag, dass, im Verhältniss zum Pflanzenreichthum der Kohlenperiode, so geringe Ueberreste i
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