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Titlebook: Hepadnaviruses; Molecular Biology an William S. Mason,Christoph Seeger Book 1991 The Editor(s) (if applicable) and The Author(s), under exc

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书目名称Hepadnaviruses
副标题Molecular Biology an
编辑William S. Mason,Christoph Seeger
视频video
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Hepadnaviruses; Molecular Biology an William S. Mason,Christoph Seeger Book 1991 The Editor(s) (if applicable) and The Author(s), under exc
描述Pioneering work on hepatitis B virus and hepatitis delta virus, and the discovery of hepatitis B-like virus in animals during the 1970‘s has been followed, over the past ten years, by an explosion of interest in how these viruses replicate, maintain chronic infections, and cause liver disease and hepatocellular carcinoma. The purpose of this book is two-fold. First, the authors of each chapter provide a summary of their specialty that will not only serve as an introduction, but will also provide the newcomer to hepatitis B virology with up-to-date information and insights into the goals and accomplishments of each area of investigation. Second, since the diversification of interests and increased specialization of hepadnaviruses researchers has reached a level where it is no longer possible for any one individual to read all the primary literature, this book will help to refocus interest on what is, after all, the major objective: to understand and ultimately treat or prevent chronic liver disease and liver cancer. Accordingly, chapters are included which span a range of interests, from the management of hepatitis B patients to new approaches to antiviral therapy, from the role of
出版日期Book 1991
关键词DNA; Karzinom; cancer; carcinoma; hepatitis; hepatitis B; hepatology; infection; infections; liver; liver dise
版次1
doihttps://doi.org/10.1007/978-3-642-76015-0
isbn_softcover978-3-642-76017-4
isbn_ebook978-3-642-76015-0Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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Assembly of Hepadnaviral Virions and Subviral Particles,ding large numbers of noninfections subviral particles as well as complete virions. Although this unusual property was among the first aspects of the viral life cycle to be discovered, it remains one of its least well understood aspects. Why do infected cells produce subviral particles? What factors
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Analysis of Hepadnavirus Gene Expression, Biology, and Pathogenesis in the Transgenic Mouse,ion the virus replicates episomally within infected cells. In chronic infection the virus may also integrate into the host cell genome. In HBV-induced hepatocellular carcinoma, integrated viral DNA sequences are virtually always present, and the viral and flanking cellular sequences may be rearrange
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Human Hepatitis Delta Virus,s been recently reviewed (B. et al. 1990; H. 1989; T. 1990a, b). The present chapter will emphasize those areas in which our perspective has recently changed and those questions about HDV which are (almost) accessible to laboratory research.
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Development of Antiviral Therapy for Chronic Infection with Hepatitis B Virus,isting chronic carriers there is no effective treatment to clear the virus and thus limit the high risk of liver diseases associated with long-term infection; chronic hepatitis, cirrhosis, and hepatocellular carcinoma. A number of recent reviews have described the limited success of current antivira
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Inherited Hepatic Enzyme Defects as Candidates for Liver-Directed Gene Therapy,developmental disability. For these defects, serious consideration must be given to any new treatment that offers the possibility of altering the extremely poor prognosis. In the desparate clinical setting of these single gene defects, two forms of therapy have recently been considered—hepatic trans
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