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Titlebook: Hemopoietic Dysplasias (Preleukemic States); Marcel Bessis,George Brecher Conference proceedings 1977 Springer-Verlag Berlin Heidelberg 19

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Preleukemia: Does it Exist? descendants of leukemic cells which have succeeded in overcoming the major final differentiation block that exists in AML. Direct evidence is quoted that red cell precursors in AML are of leukemic descent and it is claimed that the target cell of AML is the pluripotent stem cell..Next, evidence has
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Prediction of Relapse and Remission in AML by Marrow Culture Criteria of qualitative defects in the proliferation, differentiation and biophysical characteristics of leukemic colony forming cells (CFU-c) has permitted a detailed analysis of the relapse-remission status based on transition from qualitatively abnormal cell growth in vitro to a normal pattern of prolife
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The Use of the Robinson in vitro Agar Culture Assay in Adult Acute Leukemialified classification based solely on leukemic proliferation in vitro. Forty-four patients with adult acute leukemia previously untreated were included in this study and received identical chemotherapy. Three in vitro groups were recognized..The complete remission rate (CR) was 77% in the 13 patient
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Significance of PHA Induced Clonogenic Cells in Chronic Myeloid Leukemia and Early Acute Myeloid Leuemia..Phytohemagglutinin responsive cells were found in blast crisis and accelerated phase. In a small number of patients in the benign phase of their disease, colony growth with PHA was detected..A group of patients with early acute leukemia was also examined by this technique. The incidence of PHA
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Comparative Electron-Microscopic Study of the Erythrocytic Line in Refractory Anemia (Preleukemia) aectron microscopy. The results were tabulated in a semiquantitative manner and a comparison was established between the two main diagnostic groups. The following results are reported. 1. Similar nuclear and cytoplasmic abnormalities of the normoblasts were observed in preleukemia and leukemia. 2. A
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