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Titlebook: Hematologic Malignancies; Methods and Techniqu Guy B. Faguet Book 2001 Springer Science+Business Media New York 2001

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发表于 2025-3-21 16:13:55 | 显示全部楼层 |阅读模式
书目名称Hematologic Malignancies
副标题Methods and Techniqu
编辑Guy B. Faguet
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Medicine
图书封面Titlebook: Hematologic Malignancies; Methods and Techniqu Guy B. Faguet Book 2001 Springer Science+Business Media New York 2001
描述The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies. The scope of coverage is intentionally broad, ranging from routine procedures to highly sophisticated methods not currently offered by most clinical laboratories. The latter methods were selected especially to bring into focus recent advances in molecular biology that, since they provide us with strong tools for assessing the outcome of upcoming therapeutic modalities intent on disease eradication, are expected to impact the future diagnosis and management of these diseases. Thus, the c- mon thread among all chapters is clinical relevance, whether sanctioned by past experience or by the expectation that seemingly esoteric research techniques of today will prove clinically valuable in the future. Hematologic Malignancies: Methods and Techniques is primarily a compilation of methods presented in sufficient detail—by authors with extensive expertise in their field—to serve not only as a reference for seasoned research and clinical laboratory pers- nel, but also as a guide for the less experienced. Moreover, the cont
出版日期Book 2001
版次1
doihttps://doi.org/10.1385/1592590748
isbn_softcover978-1-4899-4216-6
isbn_ebook978-1-59259-074-2Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightSpringer Science+Business Media New York 2001
The information of publication is updating

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Michael Baudis,Martin Bentz some interesting results. Among these, the algorithms presented by the team of Wang are promising that it has proper computation complexity and can generate nearly optimal state estimate [194]. Based on a discrete-time linear dynamic system, Kalman filtering with intermittent observations is studie
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Cytogenetics Analysis by karyotypic changes, e.g., in cases with about 10% immature cells in the peripheral blood (PB), in chronic lymphocytic leukemia (CLL), in cases where the marrow is fibrotic or extremely hypocellular, or in determining the presence of Ph+cells in established cases of chronic myelocytic leukemia (C
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Spectral Karyotyping (SKY) of Hematologic Malignanciesrrations, particularly balanced translocations in leukemias and lymphomas, e.g., the translocation t(8;21)(q22;q22) in acute myeloid leukemia (AML) first described by Rowley et al. in 1973 (.). These balanced translocations were shown to be of etiologic as well as diagnostic, prognostic, and therape
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Molecular Genetic Methods in Diagnosis and Treatmently hereditary mutations that contribute to the genesis of these hematologic malignancies. However, for this information to be useful in treatment regimens, therapies that target or affect these growth-dysregulating mutations must be found. Because diagnosis of mutation and gene rearrangement in the
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Detecting Monoclonal Immunoglobulin andT-Cell Receptor Gene Rearrangements in B- andT-Cell Malignancement is ineffective then the other chromosome may rearrange. The . and . rearrangements will vary in DNA sequence and usually in size between lymphocyte clones and a normal individual will have a very large number of different . or . rearrangements.
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, Reverse Transcriptase-Polymerase Chain Reaction for Detecting the t(2;5) of Non-Hodgkin’s Lymphomarge-cell lymphomas. Recently, however, two recurrent genetic abnormalities in large-cell NHL-activation of the . zinc finger gene located at 3q27 (altered in approx 30% of large-cell lymphomas [.–.]) and the . fusion gene (.–.) produced by the t(2;5)-have been analyzed to now permit the identificati
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Immunohistochemistry in Leukemias and Lymphomasexpression of CD22 and CD1 1c, a monocytoid marker. Beyond its diagnostic utility, immunohistochemistry (IHC) may have prognostic significance reflecting the biologic behavior of these diseases; a case in point is CD 10 in large B-cell lymphomas, whose absence conveys a worse prognosis.
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