| 书目名称 | Hedgehog Signaling | | 副标题 | Methods and Protocol | | 编辑 | Xiaochun Li | | 视频video | | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | This detailed book explores the technical breakthroughs with biophysical and cell biological approaches that have advanced the study of molecular mechanisms underlying the generation and transduction of the hedgehog (HH) signal, indicating the important role of sterols in this pathway. Within its pages, the volume examines techniques involving several key protein components in this pathway, including HH, the signaling ligand; Dispatched, a HH secretion regulator; Patched, the receptor of HH; Smoothened, the signal transducer used to transduce the HH signal across the plasma membrane; and GLI, the transcription factor to turn on HH target genes. Written in the highly successful .Methods in Molecular Biology. series format, chapters feature introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Hedgehog Signaling: Methods and Protocols. provides researchers in clinical and basic science with a fresh and reliable reference for analyzing HH signal transduction through cell biological, biochemical, and bi | | 出版日期 | Book 2022 | | 关键词 | HH pathway; Embryonic development; Adult tissue homeostasis; Basal cell carcinoma; Sterols; Protein compo | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-0716-1701-4 | | isbn_softcover | 978-1-0716-1703-8 | | isbn_ebook | 978-1-0716-1701-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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发表于 2025-3-21 19:59:13
