| 书目名称 | Heat Shock Proteins of Malaria |
| 编辑 | Addmore Shonhai,Gregory L. Blatch |
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| 概述 | This is a novel area of malaria research that is very topical.All of the chapters are written by leaders or experts in the field.The chapters on drug discovery will appeal to the biotechnology industr |
| 图书封面 |  |
| 描述 | This book describes the role of heat shock proteins in the life cycle of malaria parasites. The work includes a general introduction on the structural and functional features of heat shock proteins. The main focus is on the role of heat shock protein families from Plasmodium falciparum, their role in protein folding and in the development of malaria pathology. The functions of individual families of heat shock proteins from plasmodium species and their cooperation in functional networks is described. Subcellular and extracellular organelles such as the apicoplast and the Maurer’s Clefts which are associated with plasmodium species, are discussed in detail. The role of heat shock proteins in the development and function of these organelles structures are highlighted. Although conceding that heat shock proteins may not be ideal antimalarial drug targets, prospects of targeting heat shock proteins in antimalarial drug discovery either directly and/or in combination therapies are explored. |
| 出版日期 | Book 20141st edition |
| 关键词 | Heat Shock Proteins and Chaperones; Plasmodium falciparum; malaria; pathogenesis; protein folding; infect |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-7438-4 |
| isbn_softcover | 978-94-024-0259-9 |
| isbn_ebook | 978-94-007-7438-4 |
| copyright | Springer Science+Business Media Dordrecht 2014 |
发表于 2025-3-21 16:59:12
