Titlebook: Heat Shock Proteins in Neuroscience; Alexzander A. A. Asea,Punit Kaur Book 2019 Springer Nature Switzerland AG 2019 Chaperone.Immunologica

Perennial长期的

Role of Heat Shock Proteins (HSP) in Neuroprotection for Ischemic Strokes in stroke models, and suggest that this approach has some translational value. Some of these pharmacological inducers have already been studied in humans for treatment of other conditions. Therefore, HSP seem to be neuroprotective, and should be further explored as a potential therapy against stro

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Molecular Chaperones and Protein Quality Control System in the Canine Model of Brain Aging and Neuro/prevention studies. The possibility to design novel therapeutic approaches, including Hsp-based therapies, may help to increase chaperone protection against proteotoxic stress occurring in human and canine brain during aging.

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Protective Role of Glial Heat Shock Proteins in Amyotrophic Lateral Sclerosisus mechanisms of motor neuron death in ALS, for example by exacerbating inflammatory signalling in glia. Since motor neurons are unable to upregulate Hsp in response to stress, it is possible they rely on surrounding glia to provide them with Hsp, and this support may be lost in ALS. Therefore, ther

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Can Hsp Targeted Gene Therapy Be a New Hope for Gliomas?n this respect, the GT appears to be a promising innovative approach against gliomas. In this chapter, we reviewed the role of overexpressed Hsp in gliomas and the importance of the GT methods for silencing of them. We emphasized the principles, expectations and limitations of the methods, and highl

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Book 2019niversities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology

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