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Titlebook: Haploidentical Transplantation; Concepts & Clinical Stefan O. Ciurea,Rupert Handgretinger Book 2018 Springer International Publishing AG,

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发表于 2025-3-21 16:25:59 | 显示全部楼层 |阅读模式
书目名称Haploidentical Transplantation
副标题Concepts & Clinical
编辑Stefan O. Ciurea,Rupert Handgretinger
视频video
概述Covers a range of clinically relevant issues in haploidentical transplantation.Provides practical support for hematologists and transplant physicians.Draws attention to the results of high-impact clin
丛书名称Advances and Controversies in Hematopoietic Transplantation and Cell Therapy
图书封面Titlebook: Haploidentical Transplantation; Concepts & Clinical  Stefan O. Ciurea,Rupert Handgretinger Book 2018 Springer International Publishing AG,
描述.In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty..
出版日期Book 2018
关键词Haploidentical Transplantation; T-Cell Alloreactivity; Myeloablative Conditioning Regimen; Non-Myeloabl
版次1
doihttps://doi.org/10.1007/978-3-319-54310-9
isbn_softcover978-3-030-09611-3
isbn_ebook978-3-319-54310-9Series ISSN 2569-1376 Series E-ISSN 2569-135X
issn_series 2569-1376
copyrightSpringer International Publishing AG, part of Springer Nature 2018
The information of publication is updating

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发表于 2025-3-21 22:55:22 | 显示全部楼层
Historical Perspective and Current Trends in Haploidentical Transplantation,f the patient needs donor-derived cellular therapies, they are easily accessed. Pioneering studies by Reisner and coworkers showed that full-donor engraftment without graft-.-host disease was achieved by escalating doses of CD34. cells in T-cell-depleted bone marrow in mouse models for T-cell-mediat
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Toward Safer CD34+ Megadose T-Cell-Depleted Transplants Following Reduced Intensity and Nonmyeloablask of higher rates of graft rejection. Thus new approaches to address this challenge are being developed. If successful, non-myeloablative haplo-HCT potentially could offer a highly attractive and safer treatment modality for patients with different hematological diseases or a platform for organ tra
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Haploidentical Transplantation Using Unmanipulated G-CSF-Primed Blood and Marrow as Allografts: Clin of studies demonstrated that unmanipulated G-CSF-stimulated haploidentical grafts can lead to rapid immune recovery, desirable health-related quality of life (QoL), and a survival rate comparable to that following HLA-matched sibling donor hematopoietic cell transplant (MSD-HCT) or HLA-matched unre
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Post-transplant Cyclophosphamide in Haploidentical Transplantationl transplantation utilizing post-transplant cyclophosphamide achieves comparable survival to HLA-matched transplantation and has thereby expanded the option of allogeneic transplantation to the vast majority of eligble recipients.
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Haploidentical Transplants and NK Cell Alloreactivityyeloid leukemia. Under T-cell-replete protocols, the benefits of NK cell alloreactivity might be expected to be antagonized/obscured as was reported in unrelated donor and cord blood transplantation. The only exception so far documented is the haploidentical hematopoietic cell transplant trial with
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