Titlebook: Handbuch Kindheits- und Jugendforschung; Heinz-Hermann Krüger,Cathleen Grunert Book 2002 VS Verlag f�r Sozialwissenschaften | Springer Fac

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mide, identified as HENECA (Fig. 17-1), which was shown to possess high affinity at A. adenosine receptors combined with a good A. versus A. selectivity[1]Table 17-1 shows the ability of HENECA to inhibit the binding of radioligands to A. and A. receptors compared with that of NECA [2], 2-[[4-(2carb

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mide, identified as HENECA (Fig. 17-1), which was shown to possess high affinity at A. adenosine receptors combined with a good A. versus A. selectivity[1]Table 17-1 shows the ability of HENECA to inhibit the binding of radioligands to A. and A. receptors compared with that of NECA [2], 2-[[4-(2carb

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August Flammervel of the plasma membrane. The pioneering studies in the early 1970s by Rall, Daly, Schwabe, and Fain clearly established that adenosine and its analogs could modulate both cyclic AMP levels in intact cells and adenylate cyclase activity in broken cell preparations. Systematic studies by Londos and

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Johanna Mierendorff,Thomas Olkr myocytes. Since its discovery, a number of factors and endogenous substances such as the ATP/ADP ratio, certain nucleotide diphosphates, Mg++, lactate, pH, protein kinase C, adenosine and bradykinin have been shown to modulate the gating properties of this channel in the heart.. Since K. channel a

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