Titlebook: Handbook of the Extracellular Matrix; Biologically-Derived F. Raquel Maia,J. Miguel Oliveira,Rui L. Reis Reference work 2024 Springer Natur

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Extracellular Matrix Isolation: Sources and Methodsdecellularization are introduced. Then, ECM isolation techniques are summarized and discussed taking into account the specifically targeted sample sources as healthy tissues, tumors, or in vitro cell cultures. Finally, the clinical applications and commercial uses of isolated ECM are discussed.

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等级的上升

Advances in ECM Protein-Based Materialsed materials can be employed in the near future. In the subsequent section, we examine the recent biomaterial developments involving ECM-derived protein-based materials. Moreover, to expand future research, we highlight the common aspects crucial for translational research relating to ECM-derived proteins.

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Protein-Based Materials as Cancer In Vitro Modelsancer research – especially in the mechanotransduction field. Therefore, alternatives are very much in need. Herein, it is presented the main proteinaceous materials used as scaffolds to model tumor development: collagen, gelatin, fibrin, and silk fibroin.

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Protein-Based Microfluidic Models for Biomedical Applicationsudy of transport properties and the biophysical and biochemical factors that control these properties. Microfluidic models can also be used to analyze, predict, and optimize the design of microfluidic networks within engineered tissues.

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conscience

Reference work 2024-derived materials, and its advanced biomedical applications. The first section is dedicated to the extracellular matrix, while the other 5 sections are each dedicated to a particular type of material. This book reports the fundamentals of the extracellular matrix and its impact on the development o

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Extracellular Matrix Remodeling on Cancer Progressions as one of the major structural components of the tumor microenvironment. The ECM undergoes continuous remodeling processes due to the progression of tumors characterized by degradation, deposition, and modification of various ECM components. The purpose of this book chapter is to review the role of ECM remodeling in the development of cancer.

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Composition of the Extracellular Matrixl established that extracellular matrices provide anchorage points to cells, relay force transmission to cells (mechanotransduction), and activate signaling pathways by interacting with cell surface receptors. This results in the control of the activities of resident cells and of the immune response