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Titlebook: Handbook of the Cerebellum and Cerebellar Disorders; Mario Manto,Donna Gruol,Roy Sillitoe Living reference work 20200th edition Ataxia.Ce

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Genes and Cell Type Specification in Cerebellar Development,ecessary to produce specific cerebellar cell types. We will then discuss two open-source cerebellar transcriptomic databases, GRiTS (Gene Regulation in Time and Space) project (.) and RIKEN FANTOM5 (./5/), which have amassed whole genome readouts of cerebellar gene expression on a daily basis during
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Hormones and Cerebellar Development,functional impairment. Estrogen and progesterone also play important roles in this process. In addition to the supply from circulation, several gonadal steroids are produced locally within the Purkinje cells (neurosteroids). This chapter discusses the effect of thyroid and steroid hormones on cerebe
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Axonal Trajectories of Single Climbing and Mossy Fiber Neurons in the Cerebellar Cortex and Nucleuseticular nucleus, pontine nucleus, dorsal column nucleus and spinal cord in the cerebellar cortex and nucleus. Furthermore, this chapter will deal with the relationship between the longitudinal cortical and nuclear compartmentations revealed by aldolase C expression and the longitudinal bands of cor
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Cerebellar Connections with Limbic Circuits: Anatomy and Functional Implications,ity, and indirect connections with the nucleus accumbens, a mesolimbic dopaminergic structure that predicts activity in a reward paradigm in limbic-related structures. Additionally, the cerebellum is interconnected with cingulate cortices that play a role in motivation and emotional drive, and with
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Delineation of Cerebrocerebellar Networks with MRI Measures of Functional and Structural Connectivices. Taken together, these results support the theory that specific neocerebellar subregions are key nodes in parallel, multisynaptic, closed-loop circuits involved in executive, mnemonic, and affective functions.
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Living reference work 20200th editionlar in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most impo
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