Titlebook: Handbook of Single-Molecule Biophysics; Peter Hinterdorfer,Antoine Oijen Book 2009 Springer-Verlag New York 2009 Biomembran.Biophysics.FRE

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Single-Molecule Imaging in Live Cells,ule detection are also described. Finally, a few representative applications using single-molecule imaging in live cells are provided to illustrate how important biological knowledge can be obtained using this powerful technique.

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Nanopores: Generation, Engineering, and Single-Molecule Applications,uidics due to their ability to control the flow of solvated ions. The combined use with atomic force and fluorescence microscopy is extending the versatility of nanopores for single-molecule research.

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Toshio Ando,Takayuki Uchihashis childhood was filled with religious observations, family celebrations, visits to and from grandparents, aunts and uncles, cousins and friends. At age thirteen Edith began to doubt her Jewish faith, and became, for all intents and purposes, an atheist.

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Folding of Proteins under Mechanical Force,. The model can provide important help for the design of a single-molecule mechanical experiment. The chapter discusses how spacer length and elasticity, as well as probe spring constant, affect the observed results. In this context it also briefly discusses the difference between atomic force microscope and optical tweezers experiments.

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,Atomic Force Microscopy of Protein–Protein Interactions,rotein unbinding measurements. Finally, the chapter summarizes recent progress in the field and shows that the AFM provides an excellent tool for probing interactions on the cell surface and for understanding the energy landscapes that govern the dynamics of protein interactions.

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