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Titlebook: Handbook of Sepsis; W. Joost Wiersinga,Christopher W. Seymour Book 2018 Springer International Publishing AG, part of Springer Nature 2018

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发表于 2025-3-21 17:19:40 | 显示全部楼层 |阅读模式
书目名称Handbook of Sepsis
编辑W. Joost Wiersinga,Christopher W. Seymour
视频video
概述Provides up-to-date information on the management of sepsis, including within the intensive care unit.Explains the use of biomarkers in the diagnosis and treatment of sepsis.Assists in the optimal use
图书封面Titlebook: Handbook of Sepsis;  W. Joost Wiersinga,Christopher W. Seymour Book 2018 Springer International Publishing AG, part of Springer Nature 2018
描述.This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio.nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseasesand internal medicine, as well as to GPs and medical students.. . . . .
出版日期Book 2018
关键词Sepsis; Intensive Care; Management; Pathogenesis; Antibiotics; Surviving Sepsis Campaign; infectious disea
版次1
doihttps://doi.org/10.1007/978-3-319-73506-1
isbn_softcover978-3-319-73505-4
isbn_ebook978-3-319-73506-1
copyrightSpringer International Publishing AG, part of Springer Nature 2018
The information of publication is updating

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发表于 2025-3-22 00:08:19 | 显示全部楼层
The Coagulation System in Sepsistissue factor pathway inhibitor. At the same time, endothelial-associated anticoagulant pathways, in particular the protein C system, are impaired by pro-inflammatory cytokines. Also, fibrin elimination is severely blocked by inactivation of the endogenous fibrinolytic system, mainly as a result of
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Vasopressors in Sepsisng effects. Adrenergic agonists are the first-line vasopressors, norepinephrine being the first-choice agent. In cases of “refractory” septic shock, adding another vasopressor with a different mechanism of action (non-adrenergic) could be considered. Vasopressin has ben shown to be a valuable altern
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Antimicrobial Therapyonotherapy is as efficient as associations supporting for a rapid de-escalation. Finally to limit antibiotic pressure, there is now a trend to propose shorter duration of treatment for the patient where the source control is adequate. Antimicrobial therapy remains a challenge in the intensive care u
发表于 2025-3-22 14:57:52 | 显示全部楼层
Sepsis in Low- and Middle-Income Countriesand middle-income countries assessing the epidemiology, long-term outcomes, and quality improvement initiatives for sepsis are urgently needed. The purpose of this review is to discuss the epidemiology of sepsis in low- and middle-income countries and the differences between these patterns and those
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