书目名称 | Handbook of Neurochemistry and Molecular Neurobiology | 副标题 | Neuroimmunology | 编辑 | Abel Lajtha (Director),Armen Galoyan,Hugo O. Besed | 视频video | | 图书封面 |  | 描述 | .This volume contains data on multiple immunomodulators, many of which are also the products of hypothalamic brain cell neurosecretion. Interleukins (IL-1a, IL-1ß, IL-2, IL-4, IL-6, TNFa), immunophylin and ubiquitin as well as proline rich peptides, comprised of 10-15 amino acids are being produced in N. Supraopticus and N. Paraventricularis and then secreted into neurohypophysis. Along the neurosecretion of the mentioned cytokines, there are other immunomodulators, the primary structure of which had been completely deciphered such as: Immunophyllins, intracellular receptors of immunosuppressors FK506, cyclosporine A., rapamicin. They are peptidyl-prolyl-cis-trans-isomerases. There are novel immunological hypothalamic factors such as ubiquitin, macrophage migration inhibitory factor (MIF), as well as Thymosin ß .4.(1-39). This data allowed us to propose the concept of neuroendocrine immune system of the brain.. | 出版日期 | Reference work 2008Latest edition | 版次 | 3 | doi | https://doi.org/10.1007/978-0-387-30398-7 | isbn_ebook | 978-0-387-30398-7 | copyright | Springer-Verlag US 2008 |
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