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Titlebook: Handbook of Lower Extremity Reconstruction; Clinical Case-Based Scott T. Hollenbeck,Peter B. Arnold,Dennis P. Orgi Book 2020 Springer Natu

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Soft Tissue Reconstruction of the Distal Third of the Lower Extremityions, favoring the use of free tissue transfer. Additional factors, such as degree of local injury, vascular insult, and co-morbid conditions, often guide surgical decision-making. Regardless of the modality, reconstructive goals remain the same: achievement of stable wound coverage without impeding functionality.
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Rachel E. Hein,Rose Tillis,Howard LevinsonIn this work we discuss the benefits of using massively parallel architectures for the optimization of Virtual Screeningmethods.We empirically demonstrate that GPUs are well suited architecture for the acceleration of non-bonded interaction kernels, obtaining up to a 260 times sustained speedup compared to its sequential counterpart version.
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Reconstruction of the Diabetic LimbSoft tissue necrosis and infection of the lower extremity are common end-stage events for the diabetic patient. Recent advances in microsurgical techniques have allowed surgeons to consider performing complex reconstructions in these patients. A carefully constructed preoperative assessment and plan are critical for success in this setting.
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Flap Principles Applied to Lower Extremity ReconstructionLower extremity reconstruction is unique in that there is high variability in tissue types and demands throughout the leg. Many soft tissue defects will involve concomitant bony injury, so an orthoplastic approach is required. Once it is determined that flap reconstruction is required, there are three main considerations:
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Principles of Local Muscle Flaps for Lower Extremity WoundsLower extremity wounds can be secondary to a variety of sources, including trauma, oncologic resection, neuropathy, or vascular disease, so they can require a variety of techniques for successful reconstruction. This chapter discusses some of the local muscle flaps generally utilized for lower extremity wounds.
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