书目名称 | Handbook of Immunosenescence | 副标题 | Basic Understanding | 编辑 | Tamas Fulop,Claudio Franceschi,Graham Pawelec | 视频video | | 概述 | Comprehensive: covers all aspects of immunosenescence in one volume.Offers a bridge in the field between research and clinical applications.Useful for anti-aging research and clinical practice.Include | 图书封面 |  | 描述 | Immunosenescence is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic s | 出版日期 | Reference work 2019Latest edition | 关键词 | Immunosenescence; Immunity; T-cells; Aging; Age-associated pathologies; Gerontology | 版次 | 2 | doi | https://doi.org/10.1007/978-3-319-99375-1 | isbn_ebook | 978-3-319-99375-1 | copyright | Springer Nature Switzerland AG 2019 |
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