书目名称 | Handbook of Immunosenescence |
副标题 | Basic Understanding |
编辑 | Tamas Fulop,Claudio Franceschi,Graham Pawelec |
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概述 | Comprehensive: covers all aspects of immunosenescence in one volume.Offers a bridge in the field between research and clinical applications.Useful for anti-aging research and clinical practice |
图书封面 |  |
描述 | .“Immunosenescence” is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. Indeed, during the almost 10 years that have passed since the first edition of this Handbook, a wealth of additional information has emerged from animal models and also from increasingly available human data. Numerous new aspects of the immune changes with aging have emerged, while others became less prominent. The application of the new multi-“omics” techniques in immunology have revolutionized our molecular understanding of basic immune mechanisms. The extended and revisited concept of Inflamm-aging sheds a new light on the intricate relationships among immunosenescence and inflamm-aging. The new concept of inflamm-aging integrates different emerging experimental data such as those pertaining to the senescence-associated secretory phenotype and responses to damage. “Geroscience” is emphasising the role of immune changes during life in all manner of age-related chronic diseases su |
出版日期 | Living reference work 20200th edition |
关键词 | Immunosenescence; Immunity; T-cells; Aging; Age-associated pathologies; Gerontology; Inflamm-aging |
doi | https://doi.org/10.1007/978-3-319-64597-1 |
isbn_ebook | 978-3-319-64597-1 |