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Titlebook: Handbook of Immunosenescence; Basic Understanding Tamas Fulop,Claudio Franceschi,Graham Pawelec Living reference work 20200th edition Imm

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书目名称Handbook of Immunosenescence
副标题Basic Understanding
编辑Tamas Fulop,Claudio Franceschi,Graham Pawelec
视频video
概述Comprehensive: covers all aspects of immunosenescence in one volume.Offers a bridge in the field between research and clinical applications.Useful for anti-aging research and clinical practice
图书封面Titlebook: Handbook of Immunosenescence; Basic Understanding  Tamas Fulop,Claudio Franceschi,Graham Pawelec Living reference work 20200th edition  Imm
描述.“Immunosenescence” is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. Indeed, during the almost 10 years that have passed since the first edition of this Handbook, a wealth of additional information has emerged from animal models and also from increasingly available human data. Numerous new aspects of the immune changes with aging have emerged, while others became less prominent. The application of the new multi-“omics” techniques in immunology have revolutionized our molecular understanding of basic immune mechanisms. The extended and revisited concept of Inflamm-aging sheds a new light on the intricate relationships among immunosenescence and inflamm-aging. The new concept of inflamm-aging integrates different emerging experimental data such as those pertaining to the senescence-associated secretory phenotype and responses to damage. “Geroscience” is emphasising the role of immune changes during life in all manner of age-related chronic diseases su
出版日期Living reference work 20200th edition
关键词Immunosenescence; Immunity; T-cells; Aging; Age-associated pathologies; Gerontology; Inflamm-aging
doihttps://doi.org/10.1007/978-3-319-64597-1
isbn_ebook978-3-319-64597-1
The information of publication is updating

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Age-Related Changes in Subpopulations of Peripheral Blood Lymphocytes in Healthy Japanese Populatiommunological parameters was steeper in females than in males (. <0.05). The T-cell proliferation index (TCPI), which was calculated based on T-cell proliferative activity and the number of T-cells, showed an age-related decline. The rate of decline in the TCPI was again steeper in males than in fema
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Older Human B Cells and Antibodies,es (IgA) or responding to T-independent bacterial polysaccharide antigens (IgG.) so we can make some inference with respect to tissue-specific immunity from a study of peripheral blood. We can also make inferences about changes in B cell development with age by looking at the repertoire of different
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Neutrophil, Basophil, and Eosinophil Granulocyte Functions in the Elderly,ng persons. However, data from different studies regarding PMN functions are still inconsistent due to different isolation and analysis techniques, contaminating cells, and preactivation. Interestingly, most of the adhesion surface molecules/receptors of PMN are not impaired in function and expressi
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