书目名称 | Handbook of HER2-targeted agents in breast cancer | 编辑 | Ricardo H Alvarez,Javier Cortés,Dimitrios Zardavas | 视频video | | 概述 | Includes the most up-to-date treatment and diagnostic guidelines, include American Society of Clinical Onocology (ASCO) and National Comprehensive Cancer Network (NCCN).In-depth discussion of the rece | 图书封面 |  | 描述 | Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies.Handbook of HER2-Targeted Agents in Breast Cancer provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings. | 出版日期 | Book 2013 | 关键词 | Biomarkers; Breast Cancer; Cancer; HER2; Oncology; pharmacotherapy | 版次 | 1 | doi | https://doi.org/10.1007/978-1-907673-94-8 | isbn_softcover | 978-1-907673-93-1 | isbn_ebook | 978-1-907673-94-8 | copyright | Springer Healthcare 2013 |
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