| 书目名称 | Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientis | | 编辑 | Younggil Kwon | | 视频video | | | 图书封面 |  | | 描述 | In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phases, the identifi- tion of the critical PK/PD/DM issues of new compounds plays an essential role in understanding their pharmacological profiles and structure-activity relationships. Owing to recent progress in analytical chemistry, a large number of compounds can be screened for their PK/PD/DM properties within a relatively short period of time. During development phases as well, the toxicology and clinical study designs and trials of a compound should be based on a thorough understanding of its PK/PD/DM properties. During my time as an industrial scientist, I realized that a reference work designed for practical industrial applications of PK/PD/DM could be a very valuable tool for researchers not only in the pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies. This book is designed specifically for industrial s | | 出版日期 | Book 2002 | | 关键词 | absorption; analytical chemistry; chemistry; development; drug; drug development; kinetics; metabolism; phar | | 版次 | 1 | | doi | https://doi.org/10.1007/b112416 | | isbn_softcover | 978-1-4757-8693-4 | | isbn_ebook | 978-0-306-46820-9 | | copyright | Springer Science+Business Media New York 2002 |
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发表于 2025-3-21 17:48:43
