Titlebook: Handbook of Antimicrobial Resistance; Matthias Gotte (Editor-in-chief),Albert Berghuis,D Reference work 2017 Springer Science+Business Med

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The Biochemistry of Quinoline Antimalarial Drug Resistance This issue is even more critical for controlling chloroquine-resistant ., about which even less is known. This review summarizes key features of quinoline antimalarial drug resistance in . malaria and suggests concepts relevant for “staying ahead of the resistance curve.”

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https://doi.org/10.1007/978-981-97-2504-5n but also in susceptibility to HIV-1 Vif-mediated degradation. The interplay between these intracellular host defenses and HIV counterstrategies is discussed in this chapter with a special emphasis on viral evolution and drug resistance.

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Michael F. Hopkins,Saul Kelly,John W. Youngmechanisms governing the relationship between the antibacterial and the bacterium. This review examines this relationship from the particular perspective of the eventual need to circumvent resistance mechanisms in order to reclaim the lifesaving value of the antibacterial chemical.

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Contribution of APOBEC3-Driven Mutagenesis to HIV Evolution and HIV Drug Resistancen but also in susceptibility to HIV-1 Vif-mediated degradation. The interplay between these intracellular host defenses and HIV counterstrategies is discussed in this chapter with a special emphasis on viral evolution and drug resistance.

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Strategies for Circumventing Bacterial Resistance Mechanismsmechanisms governing the relationship between the antibacterial and the bacterium. This review examines this relationship from the particular perspective of the eventual need to circumvent resistance mechanisms in order to reclaim the lifesaving value of the antibacterial chemical.

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Seif Emseih,Ghassan Soleiman Abu-Sittahdrug resistance is an important clinical concern. In this chapter, we discuss the principles of HBV antiviral resistance and clinical pathways for preventing the selection of drug-resistant variants, as well as appropriate management strategies for antiviral treatment failure.