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Titlebook: Hairy Roots; An Effective Tool of Vikas Srivastava,Shakti Mehrotra,Sonal Mishra Book 2018 Springer Nature Singapore Pte Ltd. 2018 Biotransf

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pRi-Transformed Plants as a Source of Secondary Metabolitesial from field-cultivated plants because of their rapid growth and often higher secondary metabolite production. Another value of the hairy roots may be their ability to regenerate whole transgenic plants. These transgenic plants are characterized by morphological changes known as hairy root syndrom
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Biotechnological Interventions of Hairy Roots of Tropane Alkaloid-Bearing Plants. Due to their anti-cholinergic activity, tropane alkaloids including hyoscyamine and scopolamine are widely used as antispasmodics and mydriatics. Because of low contents in tropane alkaloid-bearing plants, it is urgent to elevate the production of tropane alkaloids by means of biotechnology approa
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Hairy Root Cultures for Monoterpene Indole Alkaloid Pathway: Investigation and Biotechnological Prodes. These TIAs exhibit varied structural intricacy with a characteristically common tryptophan or tryptamine residue with a carbon tail of terpenoid origin derived from the dimethylallyl pyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) pathways. According to the number of isoprene units, mo
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Bioreactor Design and Analysis for Large-Scale Plant Cell and Hairy Root Cultivationites and recombinant proteins, replacing the use of whole plants. Bioreactors are used for continuous and consistent in vitro production of these low-volume high-value bioactive/therapeutic molecules from plant cells and hairy roots at large scale. The design and operation of bioreactors for plant c
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Hairy Root-Mediated Biotransformation: Recent Advances and Exciting Prospectsbiochemical stability, the large-scale production of desired metabolites, low-cost cultural requirements and hormone-independent growth made hairy root as an efficient system for synthesis of new molecules required in pharmaceuticals industry. Moreover, these characteristics make hairy root as an id
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Hairy Roots as Bioreactors for the Production of Biopharmaceuticalsst plant-made pharmaceutical for the treatment of the rare genetic disorder known as Gaucher’s disease in carrot cell cultures. The main advantages of plants compared to classical expression systems such as bacteria, yeasts or animal cell cultures are the intrinsic safety (e.g. absence of human path
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