| 书目名称 | Haemostatic Drugs | | 副标题 | A critical appraisal | | 编辑 | M. Verstraete | | 视频video | | | 图书封面 |  | | 描述 | clinical efficacy of haemostatic agents had to be published work and had to fulftl most of the following minimum requirements: (1) Quantitation ofthe measured blood loss was required, and not merely a clinical impression of the amount of blood lost, if the document pertained to a planned but «open» clinical trial. (2) Only double-blind trials with random allocation of the placebo and experimental drug to preselected patients were considered suitable for discussion, if the blood loss had not been quantitated in a prospective trial. (3) Defmition and appropriate selection of patients admitted to the trial: all inclusion and exclusion criteria used to select patients had to be mentioned in detail. (4) Once included in the trial, patients could be withdrawn only on the basis of strict criteria for withdrawal which had been defined in advance. (5) A double-blind trial had to be continued for an adequate length of time if the haemostatic agent was being assessed in the prevention of bleeding in patients with a long lasting bleeding disorder . (6) A clear and detailed statistical analysis of the results was required. Moreover, a clear distinction between the therapeutic and prophylactic v | | 出版日期 | Book 1977 | | 关键词 | alcohol; blood; clinical trial; drug; drugs; patients; prevention; tissue | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-010-1106-8 | | isbn_softcover | 978-90-247-2020-0 | | isbn_ebook | 978-94-010-1106-8 | | copyright | Martinus Nijhoff, P.O.B. 442, The Hague, The Netherlands 1977 |
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发表于 2025-3-21 19:49:52
