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Titlebook: HSP70 in Human Diseases and Disorders; Alexzander A. A. Asea,Punit Kaur Book 2018 Springer International Publishing AG, part of Springer N

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Heat Shock Proteins in the Kidney: What Is Known About Their Role in Kidney Disease of HSP in prevention of kidney injury will be crucial if translation from the laboratory to patient bedside has to occur. This article aims to be a review of heat shock protein and its relevance to kidney disease.
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Intranasal Administration of Hsp70: Molecular and Therapeutic Consequencespofuscin and modulates the activity of UPS by increasing expression of several proteasome subunits including immunoproteasome subunit β5i. Deep sequencing studies exploring brain regions of AD-model – 5XFAD mice treated with eHsp70 revealed candidate genes and signal pathways probably underlying ben
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https://doi.org/10.1007/978-94-009-7930-7 to different cellular compartments, cell death and cell cycle regulation etc. Several recent studies have suggested that Hsp70 can be a key molecule to address the major pathologies associated with neurodegenerative diseases. This chapter briefly summarizes the Hsp70 and its possible role during ne
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https://doi.org/10.1007/978-1-4613-0811-9n the role of molecular chaperones in particular heat shock protein 70 (Hsp70) in human gastrointestinal cancers along with their therapeutic targeting. This review will focus on the role of Hsp 70 and related chaperones in several gastrointestinal cancers such as pancreatic, gastric, and liver canc
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https://doi.org/10.1007/978-1-349-23540-7ssion. Genetic polymorphism has been correlated with susceptibility to many diseases and association of HSP70 polymorphism in GC is no exception. This chapter deals with various functional roles of HSP70 and its implication in tumorigenesis, particularly gastric cancer.
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https://doi.org/10.1007/978-1-4615-2093-1 molecules. MHCII peptide elution profiles obtained from cells in a steady state have also revealed the dominating presence of HSP70 derived peptides in MHC class II molecules. For these reasons HSP70 is one of the most frequent cytosolic/nuclear MHCII natural ligand sources. HSP70, when presented b
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accines, especially in the treatment of cancers and chronic viral infections. Although HSP70 constitute potent vaccine vehicles in different preclinical models, clinical studies remain disappointing. The fact that the immune properties of HSP70 have not been totally clarified may explain their relat
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