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Titlebook: HMG-CoA Reductase Inhibitors; Gerd Schmitz,Michael Torzewski Book 2002 Springer Basel AG 2002 atherosclerosis.cardiovascular.coronary arte

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书目名称HMG-CoA Reductase Inhibitors
编辑Gerd Schmitz,Michael Torzewski
视频video
概述Includes supplementary material:
丛书名称Milestones in Drug Therapy
图书封面Titlebook: HMG-CoA Reductase Inhibitors;  Gerd Schmitz,Michael Torzewski Book 2002 Springer Basel AG 2002 atherosclerosis.cardiovascular.coronary arte
描述HMG-CoA reductase inhibitors (statins) are established drugs for the treatment of hypercholesterolemia. Furthermore, they induce regression of vascular atherosclerosis as well as reduction of cardiovascular-related morbidity and death in patients with and without coronary artery disease. This book deals with statins which have substantially altered the approach to therapy of atherosclerosis and its sequelae. Emphasis is placed on the scientific background to the discoveries and the development of the therapy, including an overview of the current state of knowledge of the drugs. Clinical data are reviewed extensively. This book not only provides the reader with valuable information but also stimulates further research into the pathogenesis of atherosclerosis and themechanisms behind the action of effective statins. It sets the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating atherosclerosis and its sequelae. This topical volume...
出版日期Book 2002
关键词atherosclerosis; cardiovascular; coronary artery disease; heart; research
版次1
doihttps://doi.org/10.1007/978-3-0348-8135-7
isbn_softcover978-3-0348-9451-7
isbn_ebook978-3-0348-8135-7Series ISSN 2296-6056 Series E-ISSN 2296-6064
issn_series 2296-6056
copyrightSpringer Basel AG 2002
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The Hatfield Photographic Lunar Atlasarction or stroke is of particular relevance, because, in addition to the considerable impairment to health, it creates immense economic demands. Atherosclerosis plays a central role as an etiological component in the development of this disease. The scientific data published in the past decade are
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https://doi.org/10.1007/978-1-4614-8639-8e substantial. Consequently, both the primary and secondary prevention of CHD are major objectives of healthcare systems worldwide. Recently, large, multi-centre, clinical trials have demonstrated consistently that these objectives can be achieved though cholesterol-lowering therapy with 3-hydroxy-3
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Structure and mechanisms of action of HMG-CoA reductase inhibitors,ich remains the leading cause of death in our society [.]. The efficacy of LDL reduction in the prevention of CHD has clearly been demonstrated in a number of primary and secondary intervention trials (reviewed in reference [.]). Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductas
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