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Titlebook: HLA in Narcolepsy; Yutaka Honda,Takeo Juji Book 1988 Springer-Verlag Berlin Heidelberg 1988 Antigen.DNA.Syndrom.blood.diagnosis.syndromes

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Book 1988William C. Dement and Christian Guillemi­ nault. It succeeded the First International Symposium on Narco­ lepsy held in La Grande Motte, France, organized by Pierre Pas­ souant in July 1975 in commemoration of the 100th anniversary of the publication of Jean B. E. Gelineau‘s paper which proposed the
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Introduction,LA-associated diseases, narcolepsy has by far the strongest association with HLA. Thus narcolepsy must be considered a special disease from the molecular biologist’s point of view. In addition, the fact that narcolepsy has a close relationship with HLA genes provides promising clues for molecular bi
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Clinical Features of Narcolepsy: Japanese Experiences,al experiences with Japanese narcoleptic patients. There is a large Japanese literature on narcolepsy which has not been known to the researchers of other countries because of the language barrier. Some of these studies are cited and explained briefly. First, the symptomatology associated with narco
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HLA in Narcolepsy in Japan,ion between ankylosing spondylitis and HLA-B27. This was the strongest association between a disease and an HLA antigen for more than 10 years. The association between ankylosing spondylitis and B27 had a relative risk of 70 (Brewerton et al. 1973): a person with B27 was 70 times more likely to deve
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Positive HLA-Dw2 in Narcolepsy,. 1984; Billiard and Seignalet 1985). These findings prompted us to investigate HLA-D specificities of narcoleptics, because, in the Japanese population, HLA-D specificities that associate with HLA-DR2 have been reported to be HLA-Dw12 and less frequently Dw2, which is in contrast to the high correl
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HLA-Linked Complement Markers in Narcolepsy,ays, the classical and the alternative pathways, are known to achieve the complement activation. The structural genes for three complement components C2, C4, and factor B, which form the C3-convertases in the two pathways, were found to be situated between the loci for HLA-B and HLA-DR on chromosome
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