| 书目名称 | HLA and Disease Associations |
| 编辑 | Jawahar L. Tiwari,Paul I. Terasaki |
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| 图书封面 |  |
| 描述 | The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man |
| 出版日期 | Book 1985 |
| 关键词 | Antigen; Chromosom; DNA; Retinoblastom; Termination; Xeroderma pigmentosum; asthma; genes; genetics; infectio |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4613-8545-5 |
| isbn_softcover | 978-1-4613-8547-9 |
| isbn_ebook | 978-1-4613-8545-5 |
| copyright | Springer-Verlag New York, Inc. 1985 |
发表于 2025-3-21 16:59:02
