| 书目名称 | HIV-1 Latency | | 编辑 | Guido Silvestri,Mathias Lichterfeld | | 视频video | | | 概述 | Offers new insights into the fascinating area of HIV latency and persistence from multiple perspectives and scientific directions.Provides in-depth analyses of current concepts, paradigms and ideas th | | 丛书名称 | Current Topics in Microbiology and Immunology | | 图书封面 |  | | 描述 | .This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public. . | | 出版日期 | Book 2018 | | 关键词 | virus reservoirs; antiviral immune response; HIV eradication; Cd4+ T cell subsets; latency reactivation; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-02816-9 | | isbn_softcover | 978-3-030-13214-9 | | isbn_ebook | 978-3-030-02816-9Series ISSN 0070-217X Series E-ISSN 2196-9965 | | issn_series | 0070-217X | | copyright | Springer Nature Switzerland AG 2018 |
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发表于 2025-3-21 16:54:07
