Titlebook: HIV-1 Latency; Guido Silvestri,Mathias Lichterfeld Book 2018 Springer Nature Switzerland AG 2018 virus reservoirs.antiviral immune respons

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Molecular Control of HIV and SIV Latency,ncy virus (SIV) infection and the use of nonhuman primate (NHP) models that recapitulate many aspects of HIV-associated latency establishment and disease progression are essential tools since they allow extensive tissue sampling as well as a control of infection parameters (virus type, dose, route, and time).

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0070-217X n-depth analyses of current concepts, paradigms and ideas th.This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Speci

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Role and Function of Company Lawyers,odels have been used to predict the efficacy of potential HIV cure strategies, such as latency-reversing agents, early treatment initiation, or gene therapies, and to provide guidance for designing trials of these novel interventions.

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Mathematical Models of HIV Latency,odels have been used to predict the efficacy of potential HIV cure strategies, such as latency-reversing agents, early treatment initiation, or gene therapies, and to provide guidance for designing trials of these novel interventions.

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Book 2018ng targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex inte

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The Antiviral Immune Response and Its Impact on the HIV-1 Reservoir,he HIV-1 specific immune response, nevertheless the size and composition of the reservoir is influenced by the immune system. In this chapter, we review the different components of the HIV-1 specific immune response and discuss how the immune system can be harnessed to eradicate the virus.

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HIV-1 Latency978-3-030-02816-9Series ISSN 0070-217X Series E-ISSN 2196-9965