Titlebook: HIV Vaccines and Cure; The Path Towards Fin Linqi Zhang,Sharon R. Lewin Book 2018 Springer Nature Singapore Pte Ltd. 2018 HIV.Cure.Latency.

惰性气体

In Vitro and In Vivo Models of HIV Latencycal trials. Simian immunodeficiency virus (SIV) infection of Indian origin rhesus macaques has been well established as an informative model of HIV infection. Recent years have seen breakthroughs in ARVs that permit the potent suppression of SIV replication, enabling studies of latency and putative

致词

Measuring HIV Persistence on Antiretroviral Therapy genomic regions of HIV overestimate the size of the reservoir as they are unable to distinguish between intact and defective virus. As an alternative, sequencing the full-length integrated genome can better distinguish replication-competent provirus, but these methods may be expensive and time-cons

相一致

Clinical Interventions in HIV Cure ResearchIV latency in patients on suppressive ART. However, administration of LRAs alone has thus far not demonstrated an effect on the frequency of latently infected cells or the time to virus rebound during analytical interruption of ART. More recently, there has been an enhanced focus on immune-based the

Brain-Waves

,Correction to: HIV Persistence on Antiretroviral Therapy and Barriers to a Cure,

Pepsin

苍白

https://doi.org/10.1007/978-3-030-06031-2ed by CD8+ cytotoxic T lymphocytes (CTL). These observations and lessons learned from other viral infections have motivated the development of T-cell vaccine candidates to HIV in the preventive and especially in the therapeutic setting. While none of the T-cell vaccine concepts tested to date have s

evaculate

Traumatic-Grief

https://doi.org/10.1007/978-981-15-8558-6s that neutralize diverse HIV-1 strains develop in selected HIV-1-infected individuals. The application of single B cell-based approaches has identified many broad and potent human antibodies from infected donors. Structural studies on antibody recognition of HIV Env have revealed that these broadly

蘑菇

耐寒

https://doi.org/10.1007/978-94-6209-725-4rial conducted among serodiscordant couples. Study findings immediately informed global recommendations for the use of treatment as prevention in serodiscordant couples. The extent to which these findings are generalizable to other key populations or to groups exposed to HIV through nonsexual transm