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Titlebook: HDL Deficiency and Atherosclerosis; G. Assmann Book 1995 Kluwer Academic Publishers 1995 Lipoprotein.atherosclerosis.cardiovascular.corona

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The Future of Predictive Safety Evaluationary artery disease (CAD).. HDL are highly heterogeneous with respect to the hydrated density, size and composition of the particles. The major apolipoprotein (apo) in HDL, apoA-I, has been shown to have a strong inverse correlation with risk of CAD., whereas an inverse correlation with apoA-II level
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HDL metabolism and atherogenesis in genetically modified mice,he role of discrete genetic factors in atherogenesis. It allows study not only of the effects in mice of candidate mutations found in humans, but also through genetic synthesis it allows study of the effects of various combinations of the mutations.
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https://doi.org/10.1007/978-3-030-72815-1support the concepts that HDL-related measures are as important as LDL-related ones in predicting vascular events. Furthermore, pharmacological or genetic modification of certain plasma HDL subfractions appears to hold promise for clinical benefits that are comparable to, or perhaps exceed, those of LDLC reduction.
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