| 书目名称 | HCV: The Journey from Discovery to a Cure |
| 副标题 | Volume I |
| 编辑 | Michael J. Sofia |
| 视频video | |
| 概述 | Provides a comprehensive compilation of discoveries that led to the cure for HCV by the leading researchers in the field.Traces all aspects of HCV research that contributed to the development of key d |
| 丛书名称 | Topics in Medicinal Chemistry |
| 图书封面 |  |
| 描述 | Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study the virus spurred the search for novel direct acting antiviral drugs to cure this disease. This global effort culminated in the development of direct acting antiviral drugs that led to cure rates approaching 100% in all patient populations after only 8-12 weeks of therapy. These efforts resulted in one of the greatest achievements in public health and provides the potential for eliminating HCV as a major disease worldwide..This volume is aimed at a broad audience of academic and industrial scientists interested in the discovery and development of drugs to treat viral diseases and those interested in reading about one of the most unique accomplishments in biomedical research. The volume will provide a one of a kind reference work that highlights the many efforts, from the discovery of the HCV virus, to the invention of breakthrough medicines and their use in the real world to cure patients. It is t |
| 出版日期 | Book 2019 |
| 关键词 | HCV genome; Molecular Virology; HCV replicon system; IFN therapy; Polymerase Inhibitors; Sofosbuvir; Becla |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-28207-3 |
| isbn_softcover | 978-3-030-28209-7 |
| isbn_ebook | 978-3-030-28207-3Series ISSN 1862-2461 Series E-ISSN 1862-247X |
| issn_series | 1862-2461 |
| copyright | Springer Nature Switzerland AG 2019 |
发表于 2025-3-21 16:49:19
