书目名称 | Fungal Secondary Metabolism |
副标题 | Methods and Protocol |
编辑 | Nancy P. Keller,Geoffrey Turner |
视频video | |
概述 | Presents methods covering fungal cultivation and transformation to metabolite isolation, purification, and analysis.Features detailed and practical laboratory protocols.Includes expert tips on trouble |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .Filamentous fungi have long been known for their ability to produce an enormous range of unusual chemical compounds known as secondary metabolites, many of which have potentially useful antibiotic or pharmacological properties. Recent focus on fungal genomics coupled with advances in detection and molecular manipulation techniques has galvanized a revitalization of this field.. Fungal Secondary Metabolism: Methods and Protocols. is aimed at providing the key methodologies currently in use and necessary for accessing and exploiting the natural product information provided by the genomes of this large and varied kingdom. Written by active researchers in the field, the chapters deal with all the steps necessary, from optimization of fungal culture conditions for metabolite production, through rapid genome sequencing and bioinformatics, and genetic manipulations for functional analysis, to detection and testing of metabolites. In addition, chapters on basic science address approaches to the genetic regulation, protein biochemistry, and cellular localization of the biosynthetic pathways. Written in the highly successful .Methods in Molecular Biology™. series format, chapters include i |
出版日期 | Book 2012 |
关键词 | Filamentous fungi; Fungal culture; Fungal genomics; Fungal natural products; Metabolite production; Secon |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-62703-122-6 |
isbn_softcover | 978-1-4939-5960-0 |
isbn_ebook | 978-1-62703-122-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media, LLC 2012 |