书目名称 | Frontiers in Cancer Research | 副标题 | Evolutionary Foundat | 编辑 | Carlo C. Maley,Mel Greaves | 视频video | | 概述 | The book will identify the most important, open questions in the evolutionary biology of cancer.The book will solicit reviews from experts in the field that answer 5 questions about each individual to | 图书封面 |  | 描述 | .This is theideal book for anyone contemplating starting a career in, or shifting theircareer to, studying the dynamics that drive cancer progression and its responseto therapy. Topics include the theory and population genetics of cancers,genetic diversity within tumors (intra-tumor heterogeneity), understanding howmutant clones expand in tissues, the role of cancer stem cells in the dynamicsof tumors, the evolution of metastasis, and how to improve cancer therapy byaddressing the evolution of cancers in response to our interventions. There arealso chapters on the patterns of cancer susceptibility in humans due to amismatch between our modern environment and the environment in which ourancestors evolved, as well as a chapter on the evolution of cancer suppressionmechanisms that have evolved in different species, particularly the largelong-lived animals like elephants and whales that are better at suppressingcancers than humans. .This bookserves as a primer on the evolutionary and ecological theory of cancer- theframework upon which all the details of cancer may be hung. It is ideal foroncologists and cancer researchers interested in evolutionary theory, andevolutionary biologists | 出版日期 | Book 2016 | 关键词 | Cancer; Ecology; Evolution; Population Genetics; Oncology | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-6460-4 | isbn_softcover | 978-1-4939-8207-3 | isbn_ebook | 978-1-4939-6460-4 | copyright | Springer-Verlag New York 2016 |
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