| 书目名称 | From Malignant Transformation to Metastasis |
| 副标题 | Ion Transport in Tum |
| 编辑 | Christian Stock,Luis A. Pardo |
| 视频video | |
| 概述 | Shows a clear connection between ion transport and the initiation or progression of cancer.Highlights dysregulated expression and activity of ion channels at all stages of a tumor disease.Offers insig |
| 丛书名称 | Reviews of Physiology, Biochemistry and Pharmacology |
| 图书封面 |  |
| 描述 | .This second book of the three-volume collection "Ion Transport in Tumor Biology" helps readers gain comprehensive knowledge of the pathophysiology of cancer. The authors highlight that ion transport proteins, channels and transporters - collectively referred to as the transportome - are significantly involved in the development and progression of cancer. Nearly 90% of malignant tumor diseases originate from epithelial cells, the function of which, for the most part, is based on the transportome. This volume focuses on molecular principles by showing that dysregulated expression and/or function of ion transporters have been correlated with malignancy in the vast majority of tumor diseases..Within the story of the various chapters, the authors line out various malfunctions of the transportome and where they can be found at different stages of the metastatic cascade. The authors describe how the interactions between the tumor cells‘ transportome and the environment reinforce mesenchymal behaviour of cancer cells and contribute to their uncontrolled proliferation, migration, invasion, intra- and extravasation up to the formation of metastases. . As part of a three-volume collection, t |
| 出版日期 | Book 2022 |
| 关键词 | Epithelial Mesenchymal Transition; ion channels; malignant transformation; metastatic cascade; cell migr |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-99800-4 |
| isbn_softcover | 978-3-030-99802-8 |
| isbn_ebook | 978-3-030-99800-4Series ISSN 0303-4240 Series E-ISSN 1617-5786 |
| issn_series | 0303-4240 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 16:11:34
