| 书目名称 | Formulating Poorly Water Soluble Drugs |
| 编辑 | Robert O. Williams III,Alan B. Watts,Dave A. Mille |
| 视频video | |
| 概述 | Highlights the most recent advancements reported in the literature on technologies to improve the dissolution and bioavailability of poorly water soluble drugs.Provides a comprehensive discussion of n |
| 丛书名称 | AAPS Advances in the Pharmaceutical Sciences Series |
| 图书封面 |  |
| 描述 | The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop |
| 出版日期 | Book 20162nd edition |
| 关键词 | bioavailability; lipophilic; solubility; dissolution; formulation development; nanoparticle processes; amo |
| 版次 | 2 |
| doi | https://doi.org/10.1007/978-3-319-42609-9 |
| isbn_softcover | 978-3-319-82618-9 |
| isbn_ebook | 978-3-319-42609-9Series ISSN 2210-7371 Series E-ISSN 2210-738X |
| issn_series | 2210-7371 |
| copyright | American Association of Pharmaceutical Scientists 2016 |
发表于 2025-3-21 16:35:54
