| 书目名称 | Footmarks of Innate Immunity in the Ovary and Cytokeratin-Positive Cells as Potential Dendritic Cell |
| 编辑 | Katharina Spanel-Borowski |
| 视频video | |
| 概述 | The cyclic ovary is a site of tissue damage, repair and precisely controlled tissue homeostasis.Ovulation and luteolysis have been compared with acute and chronic inflammation respectively for a long |
| 丛书名称 | Advances in Anatomy, Embryology and Cell Biology |
| 图书封面 |  |
| 描述 | The monograph introduces innate immunity as second authority in the ovary besides the endocrine system. Innate immunity appears to orchestrate follicular atresia, follicle rupture, follicle transformation into a corpus luteum (CL) and CL regression through nonsterile inflammation and tissue repair. The concept is new. It centres on cytokeratin-positive (CK+) cells being recognized as a potential nonlymphoid dendritic cell type (DC). Part I describes morphological aspects of immune privilege starting with active hamster ovary implants into the chicken chorioallantois membrane. Follicular atresia and follicle rupture correspond with mild and moderate tissue damage in ovaries of small rodents and rabbits. Superovulations cause severe tissue damage through intraovarian oocyte release with follicle wall remnants in oedema, rupture of vessel walls and thrombosis. The complement system and neuropeptides might play regulatory roles. Part IIa analyzes intact ovaries (cows, human) for the appearance of CK+ cells. In the foetal ovary, sex cords give rise to CK+ cells in primordial follicles. In the adult ovary, CK+ cells are absent in preantral follicles and reappear in mature and regressing |
| 出版日期 | Book 2011 |
| 关键词 | Chick chorioallantoic membrane; Corpus luteum; Fetal ovary; Follicular atresia; Granulosa cells; Intra-ov |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-16077-6 |
| isbn_softcover | 978-3-642-16076-9 |
| isbn_ebook | 978-3-642-16077-6Series ISSN 0301-5556 Series E-ISSN 2192-7065 |
| issn_series | 0301-5556 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
发表于 2025-3-21 18:59:19
