书目名称 | Fifty Years of Cytochrome P450 Research | 编辑 | Hiroshi Yamazaki | 视频video | | 概述 | Covers the 50-year research history of P450 from its discovery to the most up-to-date progress.Provides a comprehensive overview of P450 research across many fields, including molecular biology, biote | 图书封面 |  | 描述 | .This book encompasses major progress and future directions in cytochrome P450 (P450) research. Included are contributions by pioneers in the discovery of P450, with chapters on the molecular and functional properties of P450 and cutting-edge applications knowledge from various fields. P450 research has its roots in metabolism, but the true beginning was in 1962 with the publication by Tsuneo Omura and Ryo Sato in .The Journal of Biological Chemistry .on their discovery of the cytochrome.. .Following this groundbreaking study, over the last half-century, research has revealed that many forms of P450 exist in animals, plants and microorganisms. P450 research has expanded into many different fields including medicine, agriculture and biotechnology and has drawn the attention of industries for its bioengineering applications, such as drug development and creation of the “blue rose”. Also, research on nuclear receptors, which has grown out of research on the regulatory mechanisms of P450 genes, has become an important area in biology, medical science, pharmacology and clinical medicine—for example, with recent developments in personalized medicines. This book will draw readers into the | 出版日期 | Book 2014 | 关键词 | Biodiversity; Biodiversity; Biosynthesis; Biosynthesis; Crystal structure; Crystal structure; Drug metabol | 版次 | 1 | doi | https://doi.org/10.1007/978-4-431-54992-5 | isbn_softcover | 978-4-431-56176-7 | isbn_ebook | 978-4-431-54992-5 | copyright | Springer Japan 2014 |
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