| 书目名称 | Fc Mediated Activity of Antibodies |
| 副标题 | Structural and Funct |
| 编辑 | Jeffrey V. Ravetch,Falk Nimmerjahn |
| 视频video | |
| 概述 | Examines the structural diversity of the Fc domain for IgG and IgE.Explores the role of Fc receptors in the context of infectious, autoimmune, and neoplastic disorders.Provides comprehensive informati |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | .This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.. |
| 出版日期 | Book 2019 |
| 关键词 | autoimmune disorders; neoplastic disorders; infectious disorders; antibody response; Fab-antigen interac |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-31053-0 |
| isbn_softcover | 978-3-030-31055-4 |
| isbn_ebook | 978-3-030-31053-0Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | Springer Nature Switzerland AG 2019 |
发表于 2025-3-21 17:07:24
