Titlebook

Gustatory

EXUDE

EAE: History, Clinical Signs, and Disease CourseEAE is a useful animal model of autoimmune disease of the central nervous system. In this chapter we discuss the history of EAE, including the original description of the model and the subsequent major developments, and then describe the usual clinical signs and disease course.

Servile

Neuroantigens in EAEThis chapter reviews briefly the biology of myelin and describes the major CNS myelin proteins, the potential neuroantigens in EAE. The genetics of the principal myelin proteins are also discussed. Myelin glycolipids with potential role in CNS demyelinating disease and the enzymes involved in their synthesis are also reviewed.

发誓放弃

B Cells and Antibodies in Experimental Autoimmune EncephalomyelitisEAE is a T cell mediated disease, but increasing evidence shows an important role for B cells and antibodies in its pathogenesis. This also reflects a role for humoral factors in the pathogenesis of multiple sclerosis. The main functions of B cells and antibodies in EAE are discussed.

ablate

The Role of Growth Factors in Experimental Autoimmune EncephalomyelitisThis chapter reviews the research done on the role of growth factor in experimental autoimmune encephalomyelitis and demonstrates the increasingly recognized therapeutic potential of growth factors in inflammatory demyelinating disease.

BARK

贪婪性

分发

Adjuvants in EAE cell-mediated immunity, including EAE. An additional adjuvant, pertussis toxin, is necessary for active EAE in mice. The mechanisms of action of adjuvants are multiple, but important actions are stimulation of proinflammatory cytokines and costimulatory molecules.

Aspiration

The Role of Astrocytes in Autoimmune Disease of the Central Nervous Systemf astrocytes includes the formation and maintenance of the blood brain barrier (BBB), and the supply of structural support and nourishment to neurons. This article will discuss the role of astrocytes in multiple sclerosis (MS) and other inflammatory autoimmune diseases of the CNS. We will address th

prostate-gland

Role of Microglia and Macrophages in Eaee cells in the normal brain and their contribution to inflammatory demyelinating disease, including their role in antigen presentation, co-stimulation, and production of cytokines and other inflammatory mediators